Ryo Kimura

Present Position Assistant Professor
Degree M.D., Ph.D.
Education Ph.D.- 2007: Department of Psychiatry, Osaka University Graduate School of Medicine
M.D.- 2002: Wakayama Medical University
M.S. – 1996: Graduate School of Agriculture, Kyoto Prefectural University
B.S. – 1994: Department of Agriculture, Kyoto Prefectural University
2012 – Present: Assistant Professor, Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University
2007 – 2012: Senior Stuff, Department of Psychiatry, Osaka General Medical Center
2003: Resident, Department of Emergency Medicine, Osaka prefectural Senri Critical Care Medical Center
2002 – 2003: Resident, Department of Psychiatry, Osaka University Hospital, Osaka, Japan
2002: Medical License (Ministry of Health, Labor, and Welfare, Japan)
2008: Designated Psychiatrist by the Japanese Ministry of Health, Labor and Welfare
2009: Japanese Board-Certified Instructor in Psychiatry
2012: Japanese Board of Medical Genetics, Clinical Geneticist

Research interest

My research interests to gain comprehensive understanding of the molecular mechanisms underlying neurodevelopmental disorders. In particular, I’m focusing on research about Williams syndrome and Autism spectrum disorder using transcriptomic approaches.


  • Member of the Japanese Society of Psychiatry and Neurology
  • Member of the Japanese Society of Human Genetics
  • Member of the Japanese Society of General Hospital Psychiatry
  • Member of the American Society of Human Genetics
  • Member of Society for Neuroscience
  1. Kimura R, Swarup V, Tomiwa K, Gandal MJ, Parikshak NN, Funabiki Y, Nakata M, Awaya T, Kato T, Iida K, Okazaki S, Matsushima K, Kato T, Murai T, Heike T, Geschwind DH, Hagiwara M. Integrative network analysis reveals biological pathways associated with Williams syndrome. The Journal of Child Psychology and Psychiatry, in press.
  2. Kimura R, Ishii Y, Tomiwa K, Awaya T, Nakata M, Kato T, Okazaki S, Heike T, Hagiwara M. Williams-Beuren syndrome as a potential risk factor for Burkitt lymphoma. Frontiers in Genetics (2018) 9:368. doi: 10.3389/fgene.2018.00368.
  3. Morihara T, Hayashi N, Yokokoji M, Akatsu H, Silverman MA, Kimura N, Sato M, Saito Y, Suzuki T, Yanagida K, Kodama TS, Tanaka T, Okochi M, Tagami S, Kazui H, Kudo T, Hashimoto R, Itoh N, Nishitomi K, Yamaguchi-Kabata Y, Tsunoda T, Takamura H, Katayama T, Kimura R, Kamino K, Hashizume Y, Takeda M. Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid beta accumulation modifier. Proc Natl Acad Sci U S A. 111(7): 2638-2643, 2014
  4. Kimura R, Ikeda S, Kumazaki H, Yanagida M, Matsunaga H. Comparison of the clinical features of suicide attempters by jumping from a height and those by self-stabbing in Japan. Journal of Affective Disorders. 150: 695-698, 2013
  5. Kimura R., Mori K., Kumazaki H., Yanagida M., Taguchi S., Matsunaga H. Treatment of delirium with ramelteon: initial experience in three patients. General Hospital Psychiatry. 33:407-409, 2011
  6. Kimura R., Yamamoto M., Morihara T., Akatsu H., Kudo T., Kamino K., Takeda M. SORL1 is genetically associated with Alzheimer disease in a Japanese population. Neuroscience Letters. 461:177-80, 2009
  7. Kimura R., Kamino K., Yamamoto M, Nuripa A, Kida T, Kazui H, Hashimoto R, Tanaka T, Kudo T, Yamagata H, Tabara Y, Miki T, Akatsu H, Kosaka K, Funakoshi E, Nishitomi K, Sakaguchi G, Kato A, Hattori H, Uema T, Takeda M. The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease. Human Molecular Genetics. 16:15-23, 2007