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Morooka S, Hoshina M, Kii I, Okabe T, Kojima H, Inoue N, Okuno Y, Denawa M, Yoshida S, Fukuhara J, Ninomiya K, Ikura T, Furuya T, Nagano T, Noda K, Ishida S, Hosoya T, Ito N, Yoshimura N, Hagiwara M.

Identification of a Dual Inhibitor of SRPK1 and CK2 that Attenuates Pathological Angiogenesis of Macular Degeneration in Mice.
Mol Pharmacol. pii: mol.114.097345.


Yoshida, M., Kataoka, N., Miyauchi, K., Ohe, K., Iida, K., Yoshida, S., Nojima, T., Okuno, Y., Onogi, H., Usui, T., Takeuchi, A., Hosoya, T., Suzuki, T., Hagiwara, M. (2015)

Rectifier of aberrant mRNA splicing recovers tRNA modification in familial dysautonomia.

Proc Natl Acad Sci U S A 112(9):2764-9


Kuwasako K, Takahashi M, Unzai S, Tsuda K, Yoshikawa S, He F, Kobayashi N, Güntert P, Shirouzu M, Ito T, Tanaka A, Yokoyama S, Hagiwara M, Kuroyanagi H, and Muto Y. (2014) RBFOX and SUP-12 sandwich a guanine base to form a stable complex and regulate tissue-specific splicing.

Nat. Struct. Mol. Biol. in press.


Yamamoto M, Onogi H, Kii I, Yoshida S, Iida K, Sakai H, Abe M, Tsubota T, Ito N, Hosoya T, and Hagiwara M. (2014) CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses.

J Clin Invest. 124(8):3479–3488.


Kurihara T, Sakurai E, Toyomoto M, Kii I, Kawamoto D, Asada T, Tanabe T, Yoshimura M, Hagiwara M, Miyata A. (2014) Alleviation of behavioral hypersensitivity in mouse models of inflammatory pain with two structurally different casein kinase 1 (CK1) inhibitors.

Mol Pain. 10:17.